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Based on domain architecture comparison with HNF4 58,59 , we engineered an NHR-49 truncation (295422) to disrupt ligand binding by removing a majority of the ligand binding domain, while retaining its analogous N-terminal, DNA-binding, hinge, and C-terminal domains (Fig

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For many people, the underlying causes of mast cell activation syndrome may include mold-related illness, chronic viral or bacterial infections, and exposure to environmental toxins

Kim YC, Won HK, Lee JW, Sohn KH, Kim MH, Kim TB, Chang YS, Lee BJ, Cho SH, Bachert C, Song WJ