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Yao et al., 2021)

Six mechanistic theories glycogen depletion, serotonin/BCAA, autonomic imbalance, central governor, HPA axis dysregulation, and Armstrong's complex systems framework

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Clinical reviews have shown that this transmucosal route successfully bypasses the destructive enzymes of the GI tract and the liver's first-pass metabolism, resulting in a rapid and statistically significant increase in blood GSH concentrations

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