PIONEER 3 study design 1,4 In a double-blind, double-dummy trial with a primary endpoint of mean change in A1C from baseline to 26 weeks, 1864 adult patients with type 2 diabetes on metformin alone or metformin with a sulfonylurea were randomized to RYBELSUS 3 mg (n=466), RYBELSUS 7 mg (n=465), RYBELSUS 14 mg (n=465), or Januvia 100 mg (n=467), all once daily
Others waste weeks of progress
Several large, randomized clinical trials are currently underway in the SURMOUNT program, aiming to determine the effectiveness of tirzepatide in promoting weight loss in overweight and obese children, individuals with obstructive sleep apnea, and those with heart failure with preserved ejection fraction [88]
Oct 2020;82:67-73
Some brands falsely claim their allulose comes from figs, raisins, or jackfruit, such as THIS and THIS
Even from reputable suppliers