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Recent Findings Since semaglutide may cause delayed gastric emptying and residual gastric contents, controversies arise on preoperative medication management, adequate preoperative fasting periods, utilization of gastric ultrasound, and rapid sequence induction and intubation to mitigate the risks of regurgitation and pulmonary aspiration of gastric contents during anesthesia care
Improves Liver Function
Several factors determine whether a peptide causes off-target hormonal activation, including receptor specificity, molecular structure, and signaling bias
Cardiovascular data on endpoints like MACE-3 or MACE-4 are presently not available yet, but an early meta-analysis demonstrated at least cardiovascular safety in patients with T2D treated with tirzepatide (78, 79)
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