A registry study in 2020 in the US showed only 40% of the patients with CKD were on ACEi/ ARBs, and smaller similar percentages (around 6%) for SGLT2i and GLP1-RA use (Nicholas, et al, Diabetes Obes Metab, 2023)
The present study provides preliminary evidence in favor of the GLP-1 based therapies in providing beneficial effects against atherosclerosis as indicated by the significant reductions in atherosclerosis markers including BNP, PAI-1 and hsCRP, besides statistically non-significant reductions in several other markers including IMT, FMD, IL-6 and TNF- were also noted
market for longer as the diabetes drug Mounjaro
18 Just as there are differences between the antihyperglycemic agents, there are inter-agent differences between the GLP-1 RAs, with established differences in their glucose-lowering, lipid-lowering and weight loss effects
Other studies have found that GLP-1 medications are associated with beneficial effects in age-related macular degeneration and glaucoma
10.3389/fendo.2019.00389 31 GaoW.JuskoW