This gradual adjustment can reduce side effects
Novo Nordisk - Regulatory Approval (December 2025): FDA approved the first oral GLP-1 for weight loss-Novo Nordisk's once-daily semaglutide pill-which launched in January 2026 [3]
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Naturally produced GLP-1 has a very short half-life of approximately 2-3 minutes
Patient input into the trial design advocated for telemetric ICP monitoring over multiple lumbar punctures to facilitate data validity and reduce patient discomfort from multiple lumbar punctures
A lot of people dont bring up diarrhea on GLP-1 medications because they feel its awkward or think its just part of it. I make a point to ask, because bowel changes can signal dehydration, food triggers, or that the dose is moving too fast