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These effects appear to be mediated in part through the recruitment and activation of fibroblasts, the primary collagen-producing cells in connective tissue

They fall into two broad categories: Prescription Drugs (Rx): - Require a doctors prescription - Used for treating specific medical conditions (Eg

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14.3%, p = 0.003) and less HCT (6.3% vs

Metformin attenuates cardiac fibrosis by inhibiting the TGFbeta1-Smad3 signalling pathway