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Its my secret weapon

Leptin does not appear to suppress GLP-1 inputs uniformly to all PVH neurons

synthetic GLP-1 analogs substituting the second amino acid for one not recognized by DPP-4 (e.g., albiglutide containing Gly [9], taspoglutide containing aminoisobutyric acid [10], and CJC-1131 containing D-Ala [11] at the second amino acid position)

Majzoub AM, Nayfeh T, Barnard A, Munaganuru N, Dave S, Singh S, et al

By influencing the brains satiety centers, semaglutide helps control food intake, promoting a healthier relationship with eating

Furthermore, it has been reported that during starvation, ketone bodies, including -hydroxybutyrate (BHB), increase and serve as an alternate source of ATP in mammals (78)