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Histological Findings For histological study after macroscopic observation, cartilage specimens from the destructive femoral area were fixed in a 10% buffered formalin solution (Sigma-Aldrich, USA) and decalcified with 8% formic acid and 8% HCl

8 Under normal conditions (no GSH deficiency), NAC does not increase total GSH, since the intracellular concentration is under feedback control

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[] Thus, the kidneys are easily damaged by ischemia or exposure to nephrotoxic substances

In contrast, two studies, including 41,046 exposed pregnancies and 131,407 comparator pregnancies, identified a statistically significant association with urinary congenital malformations (OR 1.24

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