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Fiber strategy: Increase gradually to avoid bloating
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The SURMOUNT trials showed tirzepatide producing average weight loss of 20 to 22.5 percent at the highest dose over 72 weeks, compared to semaglutide 14.9 percent in STEP 1
First, gastric emptying is already slowed
Maintaining the same caloric deficit you had on tirzepatide without accounting for the additional expenditure can push you into an excessive deficit that promotes muscle loss, fatigue, and metabolic adaptation