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study used oral administration in rodents, which is part of what attracted research interest

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This small molecule is a potent and selective non-competitive inhibitor of NNMT

Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals to evaluate carcinogenic potential have not been done

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We also acknowledge that for patients with employer-based insurance, their health plans may have additional data to help the patient understand their out-of-pocket obligation, but, as stated above, the MRFs are a key foundational data source to support driving efficiency in health care