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At our clinic we recommend at least 800 to 1000 calories per day to those on a GLP-1 and smaller, frequent meals where the protein intake is distributed throughout the day for example, 15 g for breakfast, 25 g at lunch, 30 g at dinner to enhance absorption, says Elisabetta Politi, RD, LDN, certified diabetes care and education specialist at the Duke Lifestyle and Weight Management Center in Durham, North Carolina
Eye (2020)
Mann JF, Hansen T, Idorn T, Leiter LA, Marso SP, Rossing P, et al
It has also been linked to reduced wrinkle depth and thicker skin
Its worth noting that Semaglutide GLP-1 is typically not recommended to those who are younger than 18 years old, those who have specific medical issues, or pregnant or breastfeeding women due to limited research on its effects
This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice
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