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Increased immunolabeling for OS biomarkers has been observed in the retinal tissue of dogs with acute glaucoma [213], and lower antioxidant enzymes (GPX) have been related to an increased risk of inherited glaucoma in Euraiser dogs [212]

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However, the susceptibility of the sperm oxidase activity to the membrane impermeant thiol blocking agent pCMBS (p-chloromercuriphenylsulphonate) as well as retinoic acid, distinguishes the sperm-based activity from that detected in somatic cells [37]

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