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If you are considering starting B12 supplements, particularly at high doses, discuss this with your GP or a registered pharmacist, especially if you have existing medical conditions or take other medications

Nausea and fatigue often overlap

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This ensures your body gets the right dose to fix deficiency and keep you healthy

Pernicious anemia is an autoimmune disease characterized by the absence of intrinsic factor, a glycoprotein that is necessary for vitamin B 12 absorption [25, 26]

The presence of funnel plot asymmetry also suggests potential publication bias, which warrants further scrutiny