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A Randomised Trial

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After the exclusion of 9,075 patients due to prior anti-obesity medication, and 72,731 patients for bipolar, schizophrenia, depressive disorders, anxiety and suicide ideation or attempts within 1 year before, the treatment cohort numbered 162,257 patients

Patients should also plan for hunger return, travel, holidays, stress, and life changes

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These markers included increased plasma alanine and lactate levels and the presence of organic acids, such as 3-methyl-glutaconic and dicarboxylic acids, and Krebs cycle intermediates, in the urine of these patients [69]