Despite the contradictory data regarding kidney outcomes, two surrogate outcomes benefit the most from combined therapy: the decline in eGFR slope and the reduction in urinary albumin-to-creatinine ratio
Science 336 , 12681273 (2012)
In the 2024 WADA Prohibited List (World Anti-Doping Agency, 2024c) Section 4: hormone and metabolic modulators, AIs (Subsection S4.1) and anti-estrogenic substances, including anti-estrogens and SERMs (Subsection S4.2), are prohibited at all times (in- and out-of-competition)
You can plateau on Wegovy, and a plateau does not mean you have failed or that the medicine has no effect
PMC 10225389
160,161 For example, HM15211, a triple agonist developed by Hanmi Pharmaceutical in South Korea that activates GLP-1R, GIPR and GCGR has entered early clinical trials for the treatment of obesity and non-alcoholic steatohepatitis (NASH)