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Some of the commonly reported side effects include: Nausea Diarrhea Vomiting Constipation Abdominal pain Loss of appetite Headache Fatigue Dizziness These side effects are usually mild to moderate in intensity and tend to improve over time as the body adjusts to the medication

Moreover, differences in outcome reporting, such as the use of absolute versus relative changes, or inconsistent definitions of endpoints like visceral adiposity or insulin resistance, further limited the ability to standardize data extraction and synthesis

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Community variants run 20-100 mcg/day

This study helps refine clinical guidelines

Again, this is typically dose-dependent and often resolves as water retention normalizes or with adjustments to the research protocol