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SURMOUNT and SUMMIT trials for tirzepatide document higher early discontinuation rates due to GI intolerance, though efficacy gains often justify dose adjustment rather than cessation

The lack of understanding is illustrated in survey-based studies

Thrombophilia is a condition in which a person has an increased tendency to develop abnormal blood clots due to inherited or acquired defects in the clotting process

Dual GIP/GLP-1 mechanism may produce different neurological effects than pure GLP-1 agonism

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What Therapists Are Seeing in Clinical Practice Many Certified Lymphedema Therapists report anecdotal improvements among patients who achieve meaningful weight loss while using GLP-1 medications