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Medications side effects Vitamin B12 Some other prescription medications can directly cause a vitamin B12 deficiency, such as proton pump inhibitors and metformin

PMID 270680)

He continued to say that for people with B12 deficiency, parenteral supplementation (ie not through the mouth/digestive system) therefore is a useless and expensive treatment, and if you still want it the NHS should not pay for it, you should pay for it yourself

Staggered administration by 68 hours minimizes peak plasma concentration overlap and reduces the likelihood of acute receptor saturation

& Sikiri, P

Both also play a role in immune system health