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Study results so far indicate that retatrutide is more effective than any existing weight management medication and may be almost as effective as bariatric surgery

Dihexa may also connect with intracellular signaling pathways

Ding B, Hu Y, Yuan L, Yan R-N, Ma J-H

At the time, the effort felt like compliance theater, not expected to change much behavior among GLP-1 compounders or marketers

The paper provides other measurements like changes in drinking days and changes in heavy drinking days and changes in drinks per drinking day, but its the same story: Either no benefit or no difference

For instance, ferricytochrome c reduction and adrenochrome assay measured significantly higher levels of superoxide anion in CFBE41o-cells compared to WT controls in two independent studies (de Bari et al., 2018)