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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Derry S., Wiffen P.J., Huser W., Mcke M., Tlle T.R., Bell R.F., Moore R.A

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In conclusion, these two drugs precisely maintain the homeostasis balance of muscle proteins through a dual regulatory mechanism of inhibiting decomposition and promoting synthesis, thereby exerting significant anti-atrophy effects [16]

From day 0, vehicle, MTX (7.6 mg/kg, once a week) or Epal (15.5 mg/kg, once a day) were oral administrated