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Peptides 24(2):307311

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10 More than 50% of ADEs could be prevented with safe prescribing practices

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Tryptophan Metabolism and Neurotransmission Quinolinic acid, predominantly produced by microglial cells, is also an excitatory neurotoxic compound that functions via its ability to activate the glutamate NMDA receptors, and effect that is in opposition that of kynurenic acid