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GSEA was performed using the clusterProfiler and msigdbr R packages ( Heatmaps were generated using Morpheus (Broad Institute)

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The mass spectrum of complex 2 displayed one signal with moderate intensity corresponding to the sodium adduct [M + Na] + at m/z = 376 and the another signal with high intensity corresponding to the [M L] + at m/z = 254, indicating the loss of one acetyloacetone ligand

In research on B12 deficient elderly, the administration of B12 supplementation decreased homocysteine levels and led to an improvement in cognitive ability in participants [126]

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10.1093/ijnp/pyaa060 123 Ruiz-PozoV