Therefore, LPS affects the integrity of BBB and NVU through a variety of mechanisms, providing a potential target for the treatment of related diseases
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High resolution cellular localization of the GLP-1R in monkey pancreas, gastrointestinal, cardiac and renal tissues was revealed by immunohistochemistry using the mAb 3F52 and importantly the specificity was proven by use of in situ ligand binding showing the same expression pattern
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GLP-1 works on multiple fronts: it enhances insulin secretion, inhibits glucagon production (reducing blood sugar), and delays gastric emptying, which leads to increased feelings of fullness (satiety)