Conclusion Tirzepatide demonstrated statistically significantly greater reductions in HbA1c and body weight when compared with selected GLP-1 RAs and placebo in patients with T2DM treated with basal insulin
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The recommended dose of Wegovy is 2.4 mg once weekly, reached through a 16-week dose escalation schedule (0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, then 2.4 mg)
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The sample includes 1,201 adults (n=65 in Spanish) reached through the SSRS Opinion Panel either online (n=1,176) or over the phone ( n= 25)
This kidney-protective effect appears linked to improved blood sugar control, reduced inflammation, and direct GLP-1 receptor signaling in kidney tissue