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Several peptides have demonstrated the ability to influence bone metabolism through multiple pathways, from direct osteoblast stimulation to inflammatory pathway modulation and tissue repair acceleration

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doi: 10.1146/annurev-pathol-052920-040318 188 RomagnoloA.MaseraS.MattiodaA.SupertiG.SantorelliF

Therefore, this commenter recommended CMS reconsider the emphasis on the payer-specific negotiated charge: dollar amount data element in the MRF

Neither peptide is universally better. The right choice depends on the clinical goal, the patients health history, and what other factors need to be accounted for

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