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Both medications have shown impressive results in helping people shed pounds, but there are key differences between them

At 52 weeks, the semaglutide group showed a statistically significant reduction in areal bone mineral density at the total hip (estimated treatment difference: -0.020 g/cm, p = 0.001, equating to approximately 2.6% loss) and at the lumbar spine (ETD: -0.018 g/cm, p = 0.007, approximately 2.1% loss)

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The peptide acts as a trigger

However, the lytic nature of this cell death suggests that the liberation of the intracellular content is inevitable

doi: 10.3390/ijms22105303 105