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GLP3 peptide was engineered from a GIP peptide backbone to simultaneously activate GLP-1, GIP, and glucagon receptors, while Cagrilintide peptide is a modified amylin analog designed with enhanced stability to resist the fibrillation that makes native amylin challenging to work with

doi: 10.1006/cimm.2001.1807 128 SteenbekeMDe DeckerIMarchandSGlorieuxGVan BiesenWLapauwBet al