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Analysis was performed using a reverse-phase X-select CSH C18 column (2.1 100 mm, 2.5 m

The dual mechanism also appears to provide better preservation of lean mass during weight loss, though head-to-head comparison data is still limited

The column was washed with 6 bed volumes of wash buffer (50 mM sodium phosphate, 300 mM NaCl and 100 mM imidazole, pH 7.4) and the target protein was eluted with 6 bed volumes of elution buffer (50 mM sodium phosphate, 300 mM NaCl and 300 mM imidazole, pH 7.4)

One study found a small risk increase, but some of the databases it used did not include patients over the age of 65

Purdy said its important to note that the side effect is generally mild and does not pose a significant health risk

Targher G, Valenti L, Byrne CD