The persistent state of immune activation in ME/CFS and Long COVID rapidly depletes the body's stores of essential nutrients, particularly those required for mitochondrial function
References: National Institute for Health and Care Excellence (NICE)
Preclinical and clinical data suggest that GLP-1 signaling can downregulate pro-inflammatory cytokines, such as TNF- and IL-6, inhibit NF-Bmediated inflammatory cascades, and reduce oxidative stress
The most common side effects are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort, affecting more than 1 in 10 patients
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Allergic reactions, such as a rash, swelling of the face, lips, tongue, or throat, and difficulty breathing, are rare but serious