Tachyphylaxis, the diminishing response to repeated drug exposure, appears less pronounced with Sermorelin than with direct growth hormone administration
Last reviewed: May 12, 2026 Last updated: May 12, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Weeks 1 to 4: the GI phase During the initial weeks, particularly during the 0.25 mg starting dose and the first escalation to 0.5 mg, GI side effects dominate
doi:10.1016/S0014-2999(96)00795-9 42
Common ingredients include amino acids, herbal extracts, medium-chain triglycerides (MCTs), exogenous ketones, and various plant compounds
However, if you notice that your periods are consistently more than 7 days late, or if you miss more than one cycle without a clear reason, its a good idea to schedule an appointment with one of our providers