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Participants who completed VESPER-1 were eligible to enroll in an exploratory open-label extension that evaluated higher weekly dosing (1.6 mg, 2.4 mg) and less frequent dosing (every other week and monthly)

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All treatments require evaluation and guidance from a licensed healthcare provider

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In the SUSTAIN-6 trial, there was a significantly higher event rate of diabetic retinopathy in the semaglutide-treated group compared with the control (49)