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Zielinska, M., Albrecht, J

At 0.5mg per week, 10 weeks

In some embodiments, the otic formulation or composition comprises about 0.8% by weight of the povidone

Elevation of intracellular Ca 2+ activates scramblase to ensure PS externalization, opens the Gardos channels, resulting in K + efflux and subsequent cell shrinkage, and mobilizes calpain, leading to cytoskeleton degradation and membrane microvesiculation [78]

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