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Description

Excessive ROS levels can induce cellular damage, initiating a cascade of effects that potentially culminate in tissue and organ injury ( 3.1.1 Impact of ROS on cellular function and atherosclerosis Elevated ROS can induce endothelial cell dysfunction or death, disrupting the vascular barrier and leading to vasoconstrictive and vasodilatory dysfunction, vascular smooth muscle cell proliferation and migration, inflammatory responses, and thrombosisprocesses intimately associated with various cardiovascular disorders, including atherosclerosis, hypertension, and CHD (31)

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Retrieved 15 March 2016

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[11] Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), [12] especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress

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