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Semaglutide injection efficacy is unaffected by pre-dose food intake because it enters circulation via subcutaneous tissue, not oral absorption

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Vomiting, constipation, and diarrhea also appear frequently but typically decrease after your body adapts to the medication

Most people find that nausea improves over time with proper management, including adjusting diet and eating smaller, more frequent meals

Some users find that adding specific supplements or adjusting meal timing breaks through plateaus