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Ipamorelin was investigated in a Phase II trial for postoperative ileus but did not meet its primary endpoint, and development was discontinued

These findings, in conjunction with evidence of benefits for systemic health concerns like joint health, suggest that glucosamine may potentially exert some of its protective benefits via the gut, rather than only from systemic circulation

Bettendorf M, Schmidt KG, Grulich-Henn J, et al

Tubular cell senescence and expression of TGF-beta1 and p21(WAF1/CIP1) in tubulointerstitial fibrosis of aging rats