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Foley et al

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A massive thank you to my brilliant co-authors for their dedication and persistence in getting this over the line

54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 Other studies ( n = 3465) found that metformin (15002000 mg/day) improved insulin sensitivity with or without COCPs after 6 months, 62 , 63 but had no consistent impact on body mass index (BMI), inflammatory markers, or androgens, 60 , 64 and was linked to hypoglycaemia in some cases

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A mean placebo-adjusted reduction of HbA1c up to 1.2% with the highest dose was also observed [28]