some histopathologic features that might help in differentiating the ends of the spectrum may include 1 Demonstration of small lymphocyte domination (sometimes referred to as monotonous or monomorphous population) in small cell lymphoma, compared with morphologically mixed cell populations in IBD27, 40 2 Infiltration into deeper layers (submucosa and muscle wall) in lymphocytic neoplasia27, 40, 43 3 No mucosal congestion, edema, or fibrosis in lymphocytic neoplasia, 43 compared with IBD 4 Epitheliotropism, or homing of neoplastic T lymphocytes to the mucosal epithelium in lymphocytic neoplasia 27 These features can be seen in Figure 23-22
doi:10.1002/hep.20750 6
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However, the dose & duration of treatment depends upon the medical history of the patient along with age and gender
In aggregate, they represent a massive share of the global metabolic disease burden, accounting for 38% of the worlds adult population living with obesity (Figure 2)
