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It's a bureaucratic process that can be slow and fraught with potential pitfalls

Liu, S., Gao, X., Fan, Z

Volpe, S., Lisco, G., Racaniello, D., Fanelli, M., Colaianni, V., Vozza, A., Triggiani, V., Sabb, C., Tortorella, C., De Pergola, G., & Piazzolla, G

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Lancet 379(9833):22792290 American DA (2014) Standards of medical care in diabetes2014

And it'll be very hard to tell, you know, it'll be hard even to do an observational study because the people you would have to compare with your controls would be patients who never went on the drugs and maybe never lost any weight