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Adv Clin Exp Med (2020) 29:6618

Specific transport proteins like MCT8 (monocarboxylate transporter 8) and OATP1C1 (organic anion-transporting polypeptide 1C1) (Zhang et al

Snapshot Proponents Effective for L-carnitine deficiency Supports mitochondrial health and energy function Allegedly supports liver and brain health May improve PCOS in women and semen quality and fertility in men Skeptics Many popular uses are not supported by evidence May contribute to heart disease by metabolizing TMAO Can cause nausea or stomach upset Long-term use may cause oxidative stress in the liver and blood Affects thyroid function Health Benefits of Carnitine Effective for: L-Carnitine Deficiency (Genetic) Oral and intravenous L-carnitine is effective for the treatment of primary and secondary L-carnitine deficiency due to inborn errors of metabolism (genetic)

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