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Extreme caloric restriction during the adaptation period compounds fatigue and can trigger muscle loss and metabolic slowdown

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J Neurochem 2009;109:14971507.ArticlePubMedPMC 38

Patients should be encouraged to report bowel habit changes to their GP or diabetes specialist nurse, particularly if accompanied by abdominal pain, bloating, or rectal bleeding

As a result, you naturally reduce calorie intake without forcing yourself to diet. Suppresses appetite signals : GLP-1 acts on the hypothalamus the part of your brain that controls hunger and fullness