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When lifestyle measures prove insufficient, laxatives may be appropriate: Osmotic laxatives (macrogol/polyethylene glycol preparations) are often considered first-line for chronic constipation

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Osei SP, Akomaning E, Florut TF, Sodhi M, Lacy BE, Aldhaleei WA, et al

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Side effects are common and of concern, though