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Other studies have also suggested that quercetin suppressed TGF- signaling via Sonic Hedgehog, PTEN/TIMP3 and PI3k/Akt signaling pathways (Liu et al., 2019a

New England Journal of Medicine , 373 (17), 1640-1648

2.2.3 Puerarin Puerarin is an isoflavonoid isolated from the root of the plant Pueraia and has been widely used in traditional Chinese herbal medicine for the treatment of various renal diseases, such as renal fibrosis, diabetic kidney disease, kidney stone, acute kidney injury (AKI) and CKD (Xueling et al., 2024

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