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Am J Physiol Gastrointest Liver Physiol [Internet] Am J Physiol Gastrointest Liver Physiol
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Since fundamental biochemical pathways evolved in the absence of molecular oxygen, most intracellular disulfides are rather transient and most cysteinyl residues are kept in a reduced state with the help of the thioredoxin or the glutathione/glutaredoxin system 7,63,77
As the lesion was slowly expanding during the last 3 months, there was a need to rule out melanocytic hyperplasia and/or melanoma