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Tirzepatide comparison centers on two distinct receptor strategies

2015;22:A122-A

A systematic analysis of randomized controlled trials of biologic agents for moderate to severe plaque psoriasis

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In homologous desensitization, only agonist-activated receptors are desensitized while in heterologous desensitization, both agonist-activated and non-activated receptors sharing the same signaling pathways are inactivated