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Despite the longer follow-up in STEP 5 (104 weeks versus 68 weeks in the other STEP trials), STEP 5 was again not designed or powered to assess the impact of semaglutide on the development of weight-related comorbidities such as cardiovascular disease

not significantly different)

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doi:10.2337/diabetes.50.2.291 59

Patients enrolled in trials should nonetheless report any episodes of dizziness to their trial team promptly