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Research Applications DSIP has been studied extensively in the context of sleep architecture modulation, stress response regulation, and hypothalamicpituitary signalling pathways

Moderate oxidative stress induced by HO, mitochondrial leakage, or NADPH oxidase activation promotes phosphorylation of ERK1/2, AKT, and STAT3, thereby accelerating DNA synthesis and cell-cycle progression [89]

Metabolic biomarkers of oocyte competence The metabolic profile of oocytes reflects their energetic status and developmental potential through the biochemical processes required to support fertilization and early embryonic development [113, 114]

The non-surgical management includes immobilisation in a splint, NSAIDs, and intraarticular steroid injection

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