It is necessary to acknowledge that this mechanism is totally distinct from the previous observation of the preventive effect of LASSS on HGF nitration (1:4000 ratio, without the wash-out of un-reacted LASSS
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doi:10.1016/j.autrev.2009.02.020
The animal literature is unusually consistent, though: nearly every published in vivo study used 5 mg/kg per injection, given three times on alternate days (days 1, 3, and 5, or days 14, 16, and 18 in the pulmonary fibrosis model), with effects tracked over the following three to four weeks