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What are the potential side effects of GLP-1 medications
The added glucagon receptor activation increases energy expenditure and fat oxidation, which likely explains the higher weight loss numbers in trials
Some studies have demonstrated an increased risk of depression and anxiety in individuals taking GLP-1s, and, anecdotally, some patients report experiencing emotional numbing when taking GLP-1 medications." And, she warned, the drugs could exacerbate disordered eating for some people
GLP-1 is a hormone that plays a vital role in blood sugar regulation, appetite control, and metabolism
AI-enabled in silico approaches, in tandem with high-throughput target binding assays (e.g., small-molecule microarrays) and phenotypic screens (perhaps using cAMP+ as a readout), may further uncover some of these incredibly useful molecules