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In addition, the authors provided an in-depth analysis of strategies to uncouple the cytokine response that participates in ICI-associated irAEs (247)
Valdiglesias, V
According to a recent study on The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19 (1) glutathione levels in the body were directly linked to the severity of the inflammatory response in COVID-19 patients, with the most-severe responses among those with severely depleted levels irrespective of comorbidities (2,1)
Moreover, the selenium peptide nanoparticles SeP/DOX loaded with DOX can not only increase their accumulation in tumors and rapidly release loaded drugs by identifying v3 integrins overexpressed on the surface of endothelial cells in tumors and tumor neovasculature, but also activate the immune response of NK cells through oxidative metabolites such as alkyl selenic acid to promote the improvement of anti-tumor efficacy (79)
